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Colorectal Cancer Screening Committee Virtual Meeting  – Europe 2020

CRC SC Abstracts

The meeting was held on virtually on October 9, 2020, preceding virtual UEG Week. Click on the presentation name to view and download the PDF.

*Session Presentations*

Session 1: Colorectal Cancer Screening in a COVID-19 era

• COVID-19: The forefront of virus management – Ernst Kuipers (Netherlands)
• Global news on CRC Screening in the COVID-19 era – Stephen Halloran (UK)
• Optimizing Endoscopy Efficiency and flow during and after COVID-19 – Aasma Shaukat (USA)
• COVID-19: Endoscopy services, PPE, pre-procedure testing – Asadur Tchekmedyian (Uruguay)
• Experience and Impact of Delays in Endoscopy on Bowel Cancer Screening – Siwan Thomas-Gibson (UK)
• Changes in the numbers of US patients with newly identified cancer before and during COVID-19 – Randy Howard (USA)

Session 2: Outreach & Increasing Participation in population-based programs

• Organized CRC Screening Outreach Efforts in Various Countries and Health Systems – Jason Dominitz (USA)
• Model-based comparison of measures for longitudinal screening adherence – Veerle Coupé (Netherlands)

Session 3: Looking hard for polyps

• Optimizing Polyp Resection – Heiko Pohl (USA)
• Polyp Surveillance Guidelines from the US and EU – Samir Gupta (USA)

Session 4: Programmatic issues

• Update on Early-Onset Colorectal Cancer (EOCRC) – Tom Imperiale (USA)
• Launching the European Commission Initiative on Colorectal Cancer (ECICC) – Elena Parmelli (Italy)
• Post-Colonoscopy CRC over the Globe– Matthew Rutter (UK)

Colorectal Cancer Screening Committee Meeting Barcelona – Europe 2019

CRC SC Barcelona Abstracts 

The meeting was held on October 18, 2019, preceding UEG Week in Barcelona, Spain. Click on the presentation name to view and download the PDF.

*Session Presentations*

Session 1: Colonoscopy: good, better, best? 

• Training for optical recognition of early cancer – Krijn Haasnoot (Netherlands)
• Update on the CONFIRM study – Jason Dominitz (USA)

Session 2: New light on CRC epidemiology

• Early onset colorectal cancer – Marc Bardou (France)
• Effect of CRC screening on incidence – Gavin Clark (UK)
• Comparison of screen-detected and interval cancers in FIT screening – Isabel Portillo Villares (Spain)
• Mortality due to screen-detected and interval cancer – Montse Garcia (Spain)

Session 3: The international perspective: what is happening…where? 

• Cancer screening in five continents: the IARC initiative – Eric Lucas (France)
• Update on CRC screening in Germany – Urlike Haug (Germany)
• Impact of CRC screening on incidence and mortality in the Czech Republic – Stepan Suchanek (Czech Republic)

Session 4: Issues to consider…

• Increase in faecal occult bleeding with time – Robert Steele (UK)

*Expert Working Groups*

EWG: WEO Coalition to Reduce Inequities in CRC Screening

• Agenda
• My best 10 seconds campaign – Jolanta Gore Booth (Belgium)
• Improving uptake of bowel cancer screening in the South Asian community – Lesley Smith (UK)
• Ethnic differences in bowel cancer screening awareness: findings from a pharmacy-based community survey – Andrew Prentice (UK) & Sarah Marshall (UK)
• Exploring non-attendance at colonoscopy among socioeconomically deprived and ethnically diverse populations taking part in FIT-based CRC screening – Robert Kerrison (UK)

EWG: FIT for Screening

• Agenda
• Colorectal cancer screening and choice of the positive cut–off level. Are French decision-making criteria optimal in regards to a person’s equal access to colonoscopy in regards to advanced neoplasia risk? – Aldis Kaufmanis (France)
• IFCC Update – Sally Benton (UK)

EWG: Image Enhanced Endoscopy and Endoscopic Therapy 

• Agenda
• What we need from AI in clinical practice – Tom Eelbode (Belgium)

EWG: Right-Sided Lesions and Interval Cancers

• Agenda
• Modifiable Failures in the Colorectal Cancer Screening Process and Their Association With Risk of Death – Chyke Doubeni (USA)
• How can application of the WEO consensus on PCCRC aetiology help reduce rates – Nick Burr (UK)
• PCCRC rate in the Dutch CRC program, work in progress – Manon Spaander (The Netherlands)

*Case Studies meeting*

Agenda

• IARC´s stock take of CRC Screening in Europe – Carlo Senore (Italy)
• CRC screening in middle income countries – Rolando Camacho (WHO Europe Consultant)
• Approaches to Colonoscopy Quality in Screening – Roland Valori (UK)
• Case Study: Portugal – Current Challenges – Vitor Rodrigues (Portugal)
• Case Study: Finland – New plans for FIT with a Difference (different thresholds for men and women) – Tytti Sarkeala (Finland)
• Case Study: Romania – Developing screening with help from EU and Successful Programs in Italy – Mircea Manuc (Romania)
• Case Study: Slovenia – An Early and Successful Organized Population based Screening Program – Dominika Novak-Mlakar (Slovenia)
• Case Study: Sweden: Implementation process –  Charlotta Sävblom (Sweden)

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Colorectal Cancer Screening Committee Meeting – Americas 2019

Program

The meeting was held on May 17, 2019, preceding DDW in San Diego, USA. Click on the presentation name to view and download the PDF.

*Session Presentations*

Session 1: Tribute to Professor Wendy Atkin

• Remembering Professor Wendy Atkin – David Ransohoff (USA)
• Using FIT for post-polypectomy surveillance
  – Manon Spaander (the Netherlands)
• Debate: A once only colonoscopy? Surveillance does not add much.
  True – Jeffrey Lee (USA)
  False – Samir Gupta (USA)
• Debate: Adenoma Detection Rate: Have we gone too far?
  We have – Sameer Saini (USA)
  We have not – Peter S. Liang (USA)

Session 2: Recent Advances in Science and Technology

• Young onset CRC and genetic risk factors – Douglas Corley (USA)
• CRC and microbiome signature – Mingyang Song (USA)

Session 4: Family history and Population Screening

• Family history and CRC screening: the Canadian consensus
  – Jill Tinmouth (Canada)
• Familial risk in those with a first degree relative with an advanced adenoma – Jennifer Kolb (USA)
• Cost-effectiveness and national impact of initiating average-risk CRC screening at age 45 instead of 50 – Uri Ladabaum (USA)

*Expert Working Group (EWG) Presentations*

EWG: Right-Sided Lesions and Interval Cancers

• Agenda
• PCCRC in Lynch – Francesc Balaguer (Spain)

EWG: Image Enhanced Endoscopy and Endoscopic Therapy 

• Agenda
• AI – Prediction of deep cancer invasion – Leon Moons (Netherlands)
• Priorities, challenges and barriers in implementing Artificial perception/intelligence in CRC screening and surveillance? – Michael Byrne (Canada)

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Colorectal Cancer Screening Committee Meeting – ESGE Days 2019

Program

The meeting was held on April 4, 2019, preceding ESGE Days 2019 in Prague, Czech Republic. Click on the presentation name to view and download the PDF.

*Session Presentations*

Session: Introductory session

• Principles of Organized Screening – Linda Rabeneck (Canada)
• Results of RCTs of CRC screening – Jaroslaw Regula (Poland)
• Ongoing RCTs of CRC screening – expected information
  – Rodrigo Jover (Spain)
• Original Research: Adenoma Detection Rate And Colonoscopy Indication: Beyond Screening Procedures – Carolina Mangas-Sanjuan (Spain)

Session: Colonoscopy in FIT(+) persons

• Adjusting existing colonoscopy quality indicators for FIT(+) persons
  – Rodrigo Jover (Spain)
• Need for new colonoscopy quality indicators for FIT(+) persons?
  – Cesare Hassan (Italy)
• Organizational issues for Endoscopy units providing colonoscopy in FIT(+) persons
  – Evelien Dekker (The Netherlands)
• Normal colonoscopy in FIT(+) persons: Dilemmas – Krish Ragunath (UK)
• Original research: Interval CRCs after negative FIT in a 13-year Screening Program
  – Cesare Hassan (Italy)

• Artificial intelligence – Rodrigo Jover (Spain)
• Prediction of lymph node metastasis (LNM) in T1 CRCs
  – Leon Moons (Netherlands)
• Is there justification for levels of polyp competency? – Roland Valori (UK)

Session: Updates from screening programs 

• Status of the screening program in the Canton of Vaud, Switzerland
  – Kevin Selby (Switzerland)
• Need for colorectal cancer screening in Saudi Arabia
  – Samar Alhomoud (Saudi Arabia)
• Initial findings from the Scottish Bowel Screening Program after changing to FIT
  – Judith Strachan (UK)
• Colorectal cancer screening in the regions of the Russian Federation
  – Stanislav Konovalov (Russia)
• Comparative analysis of the performance of EU screening programs
  – Carlo Senore (Italy)

• Screening start age in light of new ACS guidelines – Charles Kahi (USA)

Session: Trends and Risk stratification

• Intelligent use of FIT – Stephen Halloran (UK)

*Expert Working Group (EWG) Presentations*

EWG: WEO Coalition to Reduce Inequities in CRC Screening 

• Agenda
• Development and pilot-testing of a Colorectal Cancer Screening Decision Aid for individuals with low health literacy – Mirjam Fransen (Netherlands)
• Interventions to increase uptake in central London
  – Robert Kerrison (England)

EWG: FIT for Screening 

• Agenda
• Detectability Characteristics – Callum Fraser (UK)
• Dynamic changes of faecal haemoglobin to assess the risk of advanced colorectal lesions – Josep Auge (Spain)
• Update on the colorectal cancer screening in East Europe and Central Asia
  – Marcis Leja and Anna Krigere (Latvia)
• Status of organised screening programs with FIT around the world
  – Graeme Young (Australia)

EWG: Right-Sided Lesions and Interval Cancers

• Agenda
• PCCRC in high-risk cohorts – IBD – Nick Burr (UK)
• PCCRC in high-risk cohorts – Lynch syndrome – Francesc Balaguer (Spain)
• Right-sided cancer – is it down to a field effect? – James East (UK)

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Colorectal Cancer Screening Committee Meeting – South America 2018

Program

The meeting was held on September 28, 2018, preceding Congreso Argentino de Gastroenterología y Endoscopia Digestiva (GASTRO) 2018 in Mar del Plata, Argentina. Click on the presentation name to view and download the PDF.

• Rising Burden of Colorectal Cancer in Latin America
  – Linda Rabeneck (Canada)
• Novedades en preparación para colonoscopia
  – Eduardo Coghlan (Argentina)
• How to start a Screening Program: Uruguay Experience
  – Eduardo Fenocchi (Uruguay)
• Quality of Screening Colonoscopy – how to improve ADR
  – Roque Saenz (Chile)
• Interval Cancers – Asadur Jorge Tchekmedyian (Uruguay)
• Screening Program in Argentina: Lessons learned – Julia Ismael (Argentina)

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Colorectal Cancer Screening Committee Meeting – Americas 2018

Program

The meeting was held on June 1, 2018, preceding Digestive Disease Week® (DDW) 2018 in Washington D.C., USA. Click on the presentation name to view and download the PDF.

* Session Presentations *

Session: FIT

• Comparison of different FIT kits in the Dutch CRC screening program
  – Clasine de Klerk (Netherlands)
• Reasons for non-follow up after a positive FIT in the Dutch CRC  screening program
  – Lucinda Bertels (Netherlands)

Session: Colonoscopy Quality

• Management of pT1 polyps – Maria Pellisé (Spain)
• Colonoscopy Upskilling – Donald MacIntosh (Canada)

Session: Screening and Surveillance

• CTC vs. Colonoscopy for surveillance after CRC
  – David Weinberg (USA)
• Number of adenomas Needed to Remove (NNR) and Dwell time avoided – metrics for assessing screening Efficiency
  – Paul Pinsky (USA)
• Evaluation and comparison of the effectiveness of CRC screening tests: The IARC Handbook
  – Béatrice Lauby-Secretan (France)
• CRC screening at age 45 – What does the modeling suggest?
  – Elisabeth Peterse (Netherlands)

Session: New Technology and New Understandings/Realizations

• Rates and complications of surgery for non-malignant polyps
  – Anne Peery (USA)
• Genetics in young onset CRC – Elena Stoffel (USA)
• Deep learning for prediction of advanced neoplasia – Hyo-Joon Yang (Korea)
• Deep learning for real time histologic differentiation
  – Michael Byrne (Canada)

The WEO CRC Screening Committee 20th Anniversary
A Historical Recounting – Graeme Young (Australia)

* Expert Working Group (EWG) Presentations *

EWG: Right-Sided Lesions and Interval Cancers 

• Agenda
• Serrated polyp detection rates and factors associated with detection
  – Seth Crockett (USA)
• PCCRC: where next? – Douglas Corley, USA

EWG: Colonoscopy Screening Trials

• Agenda
• National Colonoscopy Study (NCS) – Ann Zauber, USA
• Predictive Modeling based on NCS – Reinier Meester, USA
• CONFIRM Trial – Douglas Robertson, USA
• COLONPREV Trial – Enrique Quintero, Spain
• NordiCC Trial  – Magnus Loberg, Norway

EWG: WEO Coalition to Reduce Inequities in CRC Screening

• Agenda

EWG: FIT for Screening

• Agenda
• A Swedish update from SCREESCO – Rolf Hultcrantz, Sweden
• Effectiveness of WhatsApp reminder on compliance of colorectal cancer screening – Thomas Lam, Hong Kong
• Detection in subsequent screen round in the Netherlands: results for two cut-off levels – Arthur Kooyker, The Netherlands
• The Brazilian Pilot, an update – Adriana Safatle-Ribeiro, Brazil

EWG: Surveillance after Colorectal Neoplasia 

• Agenda
• General assumptions for surveillance guidelines: endpoints, cutoffs and comparators – Rodrigo Jover (Spain)
• Performance targets for lesion detection in Surveillance
  – Uri Ladabaum (USA)
• More vs. less intensive surveillance after polypectomy: Results from microsimulation modeling – Reinier Meester (USA)

EWG: Image Enhanced Endoscopy (IEE) 

• Agenda
• Computer aided optical diagnosis of polyps – Michael Byrne (Canada)

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Colorectal Cancer Screening Committee Meeting – South America 2017

Program

The meeting was held on November 11, 2017, preceding SBAD 2017 in Brasilia, Brasil. Click on the presentation name to view and download the PDF.

Session 1

• Colorectal cancer: Why prevent it? – Linda Rabeneck (Canada)
• Screening for colorectal cancer: Global vision – Linda Rabeneck (Canada)
• How to start a screening program? – Roque Saenz (Chile)

Pilot studies in the prevention of colorectal cancer in Brazil:

• Projeto Belterra – Marcelo Averbach (Brazil)
• Prevenção do CCR no Hospital Universitário de São Paulo – Luis Masuo Maruta (Brazil)

Session 2

• What’s the best test for population screening and surveillance – Heiko Pohl (USA)
• The best imaging test for screening – Lix Alfredo Reis De Oliveira (Brazil)
• Quality of screening colonoscopy – Heiko Pohl (USA)
• Interval cancers – Heiko Pohl (USA)

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Colorectal Cancer Screening Committee Meeting – Europe 2017

Program

The meeting was held on October 27, 2017, preceding UEG Week in Barcelona, Spain. Click on the presentation name to view and download the pdf.

* Session Presentations *

Session: Novel Use of Tests

• Colon capsule in FIT+ – Gunnar Baatrup (Denmark)
• CRC risk stratification module – M Azzam Kayasseh (UAE)
• Novel optical sensor in toilet – Shlomo Lewkowicz (Israel)

Session: FIT

• Risk scoring in symptomatic patients incorporating FIT – Jayne Digby (Scotland)
• FIT: A Tale of Two Settings – Callum G Fraser (Scotland)
• Comparison of FIT performance in screening programs – Carlo Senore (Italy)

Session: Quality 

• Quality measures for individuals, institutions and programs – Roland Valori (UK)
• ESGE Quality indicators: implementation in ongoing programs – Cesare Hassan (Italy)
• Diminutive polyps and high risk status – Jasper Vleugels (Netherlands)

Session: Screening Program Updates 

• Results from the Danish colorectal screening program – Morten Rasmussen (Denmark)
• Impact of gFOBT screening in England on CRC incidence and mortality – Richard F A Logan (UK)

* Expert Working Group (EWG) Presentations *

EWG: Surveillance after Colorectal Neoplasia 

• Agenda
• Aim of the Project – Rodrigo Jover (Spain)
• Methodological Approaches – Cesare Hassan (Italy)
• Endpoints for Surveillance Studies – Michael Bretthauer (Norway)
• Potential PICOs – Carlo Senore (Italy)
• WEO Update of Evidences about Surveillance 

EWG: Right-Sided Lesions and Interval Cancers

• Agenda
• WEO Consensus on PCCRC – Iosif Beintaris (UK)
• Natural history of right-sided lesions – Jasper Vleugels (The Netherlands)
• Optimal KPI for right-sided lesions – James East (UK)
• Should right-sided lesions be surveilled differently than left-sided? – Paulina Wieszczy (Poland)
• Expert Working Group Report

EWG: FIT for Screening

• Agenda
• Summary  – Ernst Kuipers (The Netherlands), Sally Benton (UK)
• The Dutch colorectal cancer screening programme: first and second round
  – Esther Toes (The Netherlands)
• Increased Screening Cut-off Levels and Impact of a Plasma Protein Algorithm – Hans Jørgen Nielsen (Denmark)
• Comparison of surveillance in low risk adenomas: Colonoscopy vs. FIT
  – Isabel Portillo (Spain)
• The Risk of Missing Upper Gastrointestinal Cancer in Fitpositives in a Colorectal Cancer Screening Program – Manon van der Vlugt (The Netherlands)
• FIT ‐ Analytical Standardisation and Harmonisation – Sally C Benton (UK)

EWG: Coalition to Reduce Inequities in CRC Screening

• Agenda
• Socioeconomic differences – Andrea Burón (Spain)

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Colorectal Cancer Screening Committee Meeting – Asia-Pacific 2017

Program

The meeting was held on September 25, 2017, during APDW in Hong Kong. Click on the presentation name to view and download the pdf.

Session: New Technology I

• Real-world Big Data analysis and CRC Screening – Hyun-Soo Kim (Korea)
• Microbiome as a marker for CRC screening – Sunny Wong (Hong Kong)

Session: New Technology II  

• Endocuff, EndoRings, FUSE and other devices – Rupert Leong (Australia)
• A blood based biomarker for screening for colorectal cancer – KG Yeoh (Singapore)

Session: Original Research

• Results of screening and surveillance colonoscopy in young Korean adults < 50 years – Jae Myung Cha (Korea)
• Full Spectrum Endoscopy (FUSE) in the detection of inflammatory bowel disease neoplasia (FUSION) – Rupert Leong (Australia)
• Molecular imaging of colonic adenomas with fluorescent tilmanocept – Jeanette Méndez (USA)
• VIST – new imaging techniques for in vivo characterization of colorectal polyps – Ge Nan (China)
• Establishment of an algorithm to reduce the numbers of FIT screening directed colonoscopies – Hans Jørgen Nielsen (Denmark)

Session: New Practices

• Young onset CRC worldwide: is this a new trend? – Moe Kyaw (Hong Kong)
• Colonoscopy surveillance: International cohort studies – Ernst Kuipers (The Netherlands)

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Colorectal Cancer Screening Committee Meeting – Americas 2017

Program

The meeting was held on May 5, 2017, during DDW 2017 in Chicago, USA. Click on the presentation name to view and download the pdf.

* Session Presentations *

Session: Long-term risk of colorectal cancer

• Adenomas and long-term CRC risk in the PLCO trial – Benjamin Click (USA)
• Long-term CRC risk in the UK FlexiSig trial – Wendy Atkin (UK)

Session: FIT testing

• Issues and unknowns when comparing FIT tests – Esmée Grobbee (Netherlands)
• USPSTF Guidlines for CRC screening: How we arrived at what we recommended – Sue Curry (USA)

Session: Risk groups/Evaluating Risk

• Risk assessment tools – Graham Radford-Smith (Australia)
• Stool DNA testing: A Closer Look at Specificity – David Ahlquist (USA)

* Expert Working Group (EWG) Presentations *

EWG: Colonoscopy Screening Trials

• Agenda
• Global Burden of Disease – Roque Saenz (Chile)

EWG: Right-Sided Lesions and Interval Cancers

• Agenda

EWG: FIT for Screening

• Agenda
• Predictors of Timely Colonoscopy After a Positive Fecal Immunochemical Test (FIT) in the CONFIRM Study – Douglas Robertson (USA)
• Success of Mailed FIT in the United States – Samir Gupta (USA)
• Dutch roll out of FIT has led to an increase in cancer detection – Manon Spaander (The Netherlands)
• Sample Stability 16S and metagenomics analysis in OC-Sensor sample bottles – Marcis Leja (Latvia)
• FIT Resource Impact: The Calgary Experience – Robert Hilsden (Canada)

EWG: Surveillance after Colorectal Neoplasia

• Agenda
• Surveillance after neoplasia removal – Rodrigo Jover (Spain) & Uri Ladabaum (USA)
• Differences between guidelines for post-­polypectomy surveillance: is that justified? – David Lieberman (USA)
• Effect of adenoma surveillance on colorectal cancer incidence: a multicentre cohort study – Wendy Atkin (UK)
• FORTE: Five or Ten Year Colonoscopy for 1-­2 Non-­Advanced Adenomas – Robert Schoen (USA)

EWG: Image Enhanced Endoscopy (IEE)

• Agenda
• Summary Report – Heiko Pohl (USA) & David Hewett (Australia)

EWG: WEO Coalition to Reduce Inequities in CRC Screening

• Agenda

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