CRC SC Committee Material

Plenary Meeting in Washington, DC

Plenary Meeting on May 17, 2024 | Program

Session 1: Personalization based on risk assessment

• Using past screening results to adapt a personalized screening program / Reineer Meester (the Netherlands)
• Risk prediction to prescribe a life-long personalized screening program, including age to start and frequency / Ulrike Peters (USA)

Session 2: Quality Assurance in Screening

• Quality assurance with FIT: from performance to implementation / Graeme Young (Australia)
• Colonoscopy quality: Perspective from outside North America / Masau Sekiguchi (Japan)
• The new WEO EWG on Colonoscopy Quality Assurance: Disseminating best-practices worldwide / Evelien Dekker (the Netherlands)

Session 3: On Human Behavior and Programmatic Perspectives

• Applying Principles of Behavioral Economics to Colorectal Cancer Screening / Shivan Mehta (USA)
• Establishing and scaling up FIT-based screening in Mexico / Martin Lajous (Mexico)

Session 4: Emerging Screening Test

• Novel stool and blood tests – How good can they can get at detecting advanced precancerous lesions? / Wiliam Grady (USA)
• Blood based biomarkers (liquid biopsy) to screen for colorectal neoplasia: Stanford MOSAIC model / Ajitha Mannalithara (USA)
• Cost-effectiveness of blood-based colorectal cancer screening tests / Rosita van den Puttelaar (Netherlands)
• Report from the AGA Consensus Workshop on Liquid Biopsy for Average-risk Colorectal Cancer Screening / David Lieberman (USA) 

Expert Working Group Meeting in Washington, DC

EWG Meeting on May 17, 2024 | Program

Session 1A: FIT for Screening 

• FIT systematic review on use of the residual FIT buffer / Douglas Robertson (USA)
• Should the FIT threshold vary by sex? / Thomas Imperiale (USA)
• Dose-response association between fecal hemoglobin concentration in previous screening round and detection of colorectal neoplasia: a systematic review and meta-analysis / Danica van den Berg (the Netherlands)
• Using FIT to identify individuals with a very low risk of colorectal neoplasia / Graeme Young (Australia)

Session 1B: Surveillance after Colorectal Neoplasia

• Risk stratification for surveillance colonoscopy / Theodore R. Levin (USA)
• FORTE / Robert Schoen (USA)
• COOP / Theodore R. Levin (USA)

Session 2 A: Endoscopy Screening Trials 

• Overview of State of Screening Colonoscopy Trials / Robin Mendelsohn (USA)  
• SCREESCO update  /  Robin Mendelsohn (USA)  

Session 2 B: Coalition to Reduce Inequities in CRC Screening 

• Multilevel Interventions to Improve Colorectal Cancer Screening in an Urban Native American Community: A Pilot Randomized Clinical Trial / Aasma Shaukat (USA)

Session 3 A: Evaluation of New Tests

• Strategies for Evaluating New Non-Invasive Screening Tests: Plans for new publication (Special Issue Digestive Diseases and Sciences) / Robert Bresalier (USA)
• The importance of a flexible positivity threshold – report on the global survey of FIT usage / Graeme Young (Australia)

Session 3 B: PCCR & Quality in Colonoscopy

• Post-colonoscopy colorectal cancers in a national fecal immunochemical test-based colorectal cancer screening program / Pieter Wisse (Netherlands)
• Cancer Biology or Ineffective Surveillance? A multicentre retrospective analysis of colitis-associated post-colonoscopy  / Rawen Kader (UK)

Plenary Meeting in Copenhagen, Denmark

Plenary Meeting on October 13, 2023 | Program

Session 1: Insights from ongoing CRC screening programs

• CRC screening pilot in Romania - a presentation of the performance of the program / Mircea Manuc (Romania)

Session 2: Management of screen-detected lesions

• Staging of rectal polyps: is there room for improvement? / Maria Pellise (Spain)

Session 3: Novel CRC screening tests

• The NCI/NIH (USA) initiative on blood based multi-cancer detection (MCD) tests / David Weinberg (USA)
  
• The next generation Cologuard test - will this stimulate its use in Europe? / Kevin Selby (Switzerland)

Session 4 Quality in CRC screening

• Developing uniform global standards for colonoscopy quality: Which, defining threshold values, and how to make practical? / Douglas E. Corley (USA)
• Territorial equity in colonoscopy KPI in a national screening program / Antoni Castells (Spain)
• Implementation of the PSPDR alongside the ADR: a dire necessity or superfluous hassle? /Joep IJspeert (Netherlands)

Expert Working Group Meetings in Copenhagen, Denmark

EWG Meeting on October 13, 2023 | Program

Session 1: FIT for Screening

• An evaluation of personalized benefits and harms of colorectal cancer screening in order to facilitate informed decision making on participation in the CRC screening program / Francine van Wifferen (Netherlands)
• Risk prediction algorithms for CRC screening / Christina Therkildsen (Denmark)

• Declining trend in the participation rate in the FIT-based colorectal cancer screening program in the Netherlands - what about other screening programs? / Esther Toes-Zoutendijk (Netherlands)
• FIT can be used in CRC screening to eliminate current disadvantages for women / Callum Fraser (UK)

Session 2a: PCCRC & Quality in Colonoscopy

• Are ADRs at screening associated with CRC risk and death at 17 years? / Kate Wooldrage (UK)

Session 2b: Coalition to Reduce Inequities in CRC Screening

• Who should be targeted first: background risk of non-participants / Hilliene van de Schootbrugge - Vandermeer (Netherlands)
• How to increase participation in colorectal cancer screening – including among vulnerable citizens / Mette Bach Larsen (Denmark)
  
• London Bowel Cancer Screening Social Marketing Campaign - results of a regional intervention to reduce inequalities / Josephine Ruwende (England)

Session 3a: Surveillance After Colorectal Neoplasia

• Use of molecular markers as predictors of metachronous neoplasia / Rodrigo Jover (Spain)
• FIT for surveillance / Joaquin Cubiella (Spain)

Session 3b: Artificial Intelligence and Polyp Management

• Polyp sizing and pathology for diminutive polyps - Do we still need pathology? / Daniel von Renteln (Canada)

Hybrid Plenary Meeting in Chicago, USA

Plenary Meeting on May 5, 2023 | Program

Session 1: CRC Screening policy update

• English national PCCRC audit data / Roland Valori (UK)
• Real-time capture of the patient-reported experience / Alan Smith (Ireland)
• Support for jurisdictions looking to implement screening, including lessons learned in NZ / Susan Parry (New Zealand), Linda Rabeneck (Canada)

Session 2: NordICC at 10 years: Implications for screening colonoscopy

• NordICC at 10 years: Results, Surprises, and Questions for the Investigators / Uri Ladabaum (USA)

Session 3: The many facecs of FIT

• Beyond Positive vs. Negative: Cumulative fecal Hb level for risk prediction / Carlo Senore (Italy)

Session 4: Emerging tests and precision screening

• The New Test EWG Consensus v2 is done: What’s next and how can we have real-world impact? / Robert Bresalier (USA)
• Shifting from universal to precision screening / Chen-Yang Hsu (Taiwan)

Expert Working Group Meetings in Chicago, USA

EWG Meeting on May 5, 2023 | Program

Session 1: CRC Surveillance after Colorectal neoplasia

• Update on FORTE / Robert Schoen (USA)

Session 2: FIT for screening

• New Zealand Bowel Screening Programme Post Colonoscopy CRC -lessons / Susan Parry (New Zealand)
• Impact of indication for procedure, setting and patient characteristic on colonoscopy colorectal cancer detection in Ontario, Canada / Catherine Dubé (Canada)

Session 3: PCCR & Quality in Colonoscopy

• Post-colonoscopy Colorectal Cancers in a Large Integrated Health Care Center: Tumor Characteristics, Survival, and Risk Factors for Mortality / James Kang (UK)
• Combatting PCCRC – an educational experience / Silvia Sanduleanu (Netherlands)

Session 5: Polyp detection, characterization, resection adn AI

• Update on the WEO consensus statement for complex polypectomy / Yutaka Saito (Japan)
• Small steps, big impact, how AI assisted colonoscopy can help reducing carbon footprint / Heiko Pohl (USA)

Virtual CRC SC Meeting at APDW 2022 in Xi’an, China

CRC SC Meeting on November 17, 2022 | Program

• Third Asia Pacific Consensus Recommendations on Colorectal Cancer Screening

Hybrid Plenary Meeting in Vienna, Austria

Plenary Meeting on October 7, 2022 | Program

Session 1: CRC Screening policy update

• Global CRC incidence and mortality trends / Linda Rabeneck (Canada)
• EU Recommendations on cancer screening / Michael Kaminski (Poland)

Session 2: Risk stratification in CRC screening

• Colonoscopy Prioritization / Revital Kariv (Israel)

Session 3: Participation in CRC screening

• The role of Defensive Information Processing in population-based colorectal cancer screening uptake / Nick Clarke (Ireland)
• Reducing the footprint of CRC screening / Iris Seriese (Netherlands)

Session 4: Screen detected CRC

• CRC: indication for ESD / Yutaka Saito (Japan)
• Screen detected T1 CRC in the Netherlands / Lisa van der Shee (Netherlands)

Expert Working Group Meeting in Vienna, Austria

EWG Meeting on October 7, 2022

FIT for Screening

• Association of Fecal Immunological Test with the risk of gastroesophageal cancer within a population with an intermediate risk for cancer / Zohar Levi (Israel)
• A survey aimed to collect quantitative information about screening activity during the pandemic emergency / Carlo Senore (Italy)

PCCRC & Quality in Colonoscopy

• Molecular pathways in post-colonoscopy versus prevalent colorectal cancers: results from a population-based cohort study / Beatriz Carvalho (Netherlands)

Inequities in CRC Screening

• Colorectal Cancer Screening during Pandemic / Samar Alhomoud (Saudi Arabia)
• Participation during the Covid pandemic / Morten Rasmussen (Denmark)
• Factors associated with participation in the Dutch CRC screening program / Esther Toes-Zoutendijk (Netherlands)

Surveillance after Colorectal Neoplasia

• Post-surgery endoscopy surveillance for colorectal cancer / Giulio Antonelli (Italy)
• Surveillance after endoscopic excision of pT1 malignant polyp. Is that different? / Maria Pellisé & Rodrigo Jover (Spain)

Polyp detection, characterization, resection and AI

• CADe, CADx – how good is it and how good should it be? / Roupen Djinbachian (Canada)
• Beyond AI diagnosis: New evidence of ESD, suggesting a refined management of colorectal neoplasm / Yutaka Saito (Japan)

Hybrid Plenary Meeting in San Diego, USA

Plenary Meeting on May 20, 2022 | Program

Session 1: Early-onset

• Prevalence of colorectal neoplasia in young individuals / GIQuIC: Yield of screening 45–49-year-olds / Parth Trivedi (USA)
• Fight CRC: Integrating Stakeholders with Research Initiatives in Early-onset Colorectal Cancer / Jennifer Kolb, Caitlin Murphy (USA)
• Potential Effects of Lowering Colorectal Cancer Screening Age to 45 Years on Colonoscopy Demand, Case Mix, and Adenoma Detection Rate / Seth Crockett (USA)

Session 2: New tests

• Review on regional variation in microbiome / Mingyang Song (USA)
• Update for the WEO Expert Working Group on New Test Evaluation: Assessing the cost effectiveness of new tests / Uri Ladabaum (USA)

Session 3: Risk-based screening and encouraging uptake

• Risk-based screening versus FIT for detecting advanced neoplasia: A within group comparison in a randomized controlled trial / Tim Kortlever (Netherlands)
• Using Facebook to promote the uptake of colorectal cancer screening / Arlinda Ruco (Canada)
• M-TICS: A study to assess the effectiveness of SMS-based interventions to increase participation in a population-based colorectal cancer screening program / Montse Garcia (Spain)

Session 4: Emerging trends

• Green endoscopy / Heiko Pohl (USA)
• How to measure equity by race and ethnicity and socio-economic status, and what to do about the results. An update along with results from recent letter in NEJM / Chyke Doubeni (USA)
• Serrated polyp detection and risk of interval post-colonoscopy colorectal cancer: a population-based study / David van Toledo (Netherlands)
• Comparing Colorectal Cancer Screening Outcomes in the International Cancer Screening Network (ICSN): A Consortium Proposal / Iris Lansdorp-Vogelaar (Netherlands)

Hybrid Expert Working Group Sessions in San Diego, USA

EWG sessions on May 20, 2022 | Program

Session 1: EWGs Surveillance after Colorectal Neoplasia and Polyp detection, characterization, resection and AI

• Why people at high risk remain at high risk after polyp excision / Samir Gupta (USA)
• EPoS study update / Rodrigo Jover (Spain)
• Incomplete resection, complete resection and polyp recurrence / Roupen Djinbachian (Canada)
• Benefits and limitations of using CADx in colonoscopy: learning from the first comparative clinical trial / Sophie Williams (UK)

Session 2: EWGs FIT for Screening and Evaluation of new tests

• A trial of 50,000 US Veterans who were randomized to colonoscopy vs. FIT / Jason Dominitz (USA)
• Adherence to FIT Screening / Paul Limburg (USA)
• Cost effectiveness of outreach strategy for stool-based CRC screening / Durado Brooks (USA)
• Two-sample Fecal Immunochemical Testing as a Tool to avert Colonoscopy in Symptomatic Patients / Pieter Wisse (Netherlands)
• Progress with consensus process | Uri Ladabaum’s presentation from plenary meeting / Robert Bresalier (USA)

Session 3: Case Studies: Impact of COVID-19

• Impact of COVID Pandemic on FIT-Based CRC Screening Programs in 3 Countries: What Does Modeling Tell Us? / Iris Lansdorp-Vogelaar (Netherlands)
• Impact of COVID Pandemic on CRC Screening Ontario: What Did We Learn? / Jill Tinmouth (Canada)
• Impact of COVID Pandemic on FIT Use, Colonoscopy, and Neoplasia Detection: Lessons from Kaiser Permanente / Theodore Levin (USA)